Protein Info for MPMX19_02463 in Azospirillum sp. SherDot2

Annotation: Heme exporter protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details amino acids 127 to 153 (27 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 193 to 216 (24 residues), see Phobius details PF03379: CcmB" amino acids 4 to 217 (214 residues), 278.4 bits, see alignment E=1.8e-87 TIGR01190: heme exporter protein CcmB" amino acids 7 to 217 (211 residues), 278.3 bits, see alignment E=1.9e-87

Best Hits

Swiss-Prot: 54% identical to CCMB_SHIFL: Heme exporter protein B (ccmB) from Shigella flexneri

KEGG orthology group: K02194, heme exporter protein B (inferred from 98% identity to azl:AZL_027980)

MetaCyc: 54% identical to cytochrome c maturation protein B (Escherichia coli K-12 substr. MG1655)
RXN-21408

Predicted SEED Role

"ABC transporter involved in cytochrome c biogenesis, CcmB subunit" in subsystem Biogenesis of c-type cytochromes

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (221 amino acids)

>MPMX19_02463 Heme exporter protein B (Azospirillum sp. SherDot2)
MSRFLRLVARDLRLALRQGSDATIAVMFFVLCVVLFPFGVGPEPNILARIAAGVIWVAAL
LASLLSLERLFQTDYEDGSLELLSLSPLPLEAAVLAKTLAHWLVTGVPLIVAAPLLAVLL
NMDAQGFGVLVLTLTLGTPILSLIGAIGAALTLGARRGGVLLSLLILPLYIPVLIFGAGA
IDAAINGLTPRPHLLLLAGILAAALPLAPWAGAAALRQAVE