Protein Info for MPMX19_02380 in Azospirillum sp. SherDot2

Annotation: Periplasmic pH-dependent serine endoprotease DegQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR02037: peptidase Do" amino acids 60 to 378 (319 residues), 439.9 bits, see alignment E=5.1e-136 PF13365: Trypsin_2" amino acids 113 to 248 (136 residues), 122.2 bits, see alignment E=7.4e-39 PF00089: Trypsin" amino acids 114 to 273 (160 residues), 75.9 bits, see alignment E=1.1e-24 PF00595: PDZ" amino acids 285 to 366 (82 residues), 44.4 bits, see alignment E=4.3e-15 PF13180: PDZ_2" amino acids 287 to 377 (91 residues), 58.2 bits, see alignment E=2.2e-19 PF17820: PDZ_6" amino acids 314 to 367 (54 residues), 41 bits, see alignment 3.5e-14

Best Hits

KEGG orthology group: K04772, serine protease DegQ [EC: 3.4.21.-] (inferred from 94% identity to azl:AZL_002020)

Predicted SEED Role

"HtrA protease/chaperone protein / Serine protease (Protease DO) (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>MPMX19_02380 Periplasmic pH-dependent serine endoprotease DegQ (Azospirillum sp. SherDot2)
MKMAVRPVMFAAAVGIAALTGGALVAPADSALGRIGSAIGLGASPAEAALPLGAVGGGTI
APMLEQVTPAVVNISVLSQAPQAENPLLRDPFFRRFFNLPDQMPQSKPQVSAGSGVIIDA
RNGYVVTNNHVVENAQEIAVTLKDRRRLRAKLIGRDAATDIALLQIKADGLAALSIGDSD
RTKVGDFVVAIGNPFGLGQTVTSGIVSAMGRSGLKIEGYEDFIQTDASINPGNSGGALVN
FQGELIGINTAIIGPAGGSVGIGFAVPVSIVRSVVEQLREYGEVRRGRLGVAIQDLTPDL
AESMSLKGDEGALIAKIERGSPADSGGLRSGDVVIAVDGRPVRSATDFRNRIGLLRVGTP
VQLTVMREGGQKSVTVRTQR