Protein Info for MPMX19_02121 in Azospirillum sp. SherDot2

Annotation: putative trans-aconitate 2-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 PF13489: Methyltransf_23" amino acids 21 to 177 (157 residues), 47.8 bits, see alignment E=4.1e-16 PF13847: Methyltransf_31" amino acids 38 to 143 (106 residues), 34.7 bits, see alignment E=4.1e-12 PF13649: Methyltransf_25" amino acids 39 to 128 (90 residues), 54.6 bits, see alignment E=4.4e-18 PF08241: Methyltransf_11" amino acids 40 to 131 (92 residues), 39.9 bits, see alignment E=1.7e-13 PF08242: Methyltransf_12" amino acids 41 to 130 (90 residues), 40.4 bits, see alignment E=1.3e-13

Best Hits

Swiss-Prot: 37% identical to TAM_STRAW: Trans-aconitate 2-methyltransferase (tam) from Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

KEGG orthology group: K00598, trans-aconitate 2-methyltransferase [EC: 2.1.1.144] (inferred from 37% identity to bfa:Bfae_17170)

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.144

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>MPMX19_02121 putative trans-aconitate 2-methyltransferase (Azospirillum sp. SherDot2)
MTRATTADPNAFATIDVLRRRPVMDLTAALPLSLTPHTVVDLCCGAGQLSRLLAARWPKA
DVLAVDHSPAMLRWAADTPSRVRYQQADLGEWRPHWPVDLIISAGGLHHVGGHERLLPDL
LQSLGPGGILAVALPRPQAQTAHRLLLETAADGPWSDRLHDVWPAAERTESPSHDAQDYY
DWLAPQGAVIDLWETEYFHALDGDVPLLQWLHQSALVPVMDRLAGPDLDRFLAAYRRRLE
TAYPEHSSGGALIPTKWLLLVAQV