Protein Info for MPMX19_01862 in Azospirillum sp. SherDot2

Annotation: Sensor histidine kinase TmoS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 PF00072: Response_reg" amino acids 4 to 118 (115 residues), 79.4 bits, see alignment E=3.5e-26 TIGR00229: PAS domain S-box protein" amino acids 147 to 266 (120 residues), 40.6 bits, see alignment E=1.3e-14 PF02518: HATPase_c" amino acids 425 to 552 (128 residues), 81.3 bits, see alignment E=1.1e-26

Best Hits

KEGG orthology group: None (inferred from 87% identity to azl:AZL_022650)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>MPMX19_01862 Sensor histidine kinase TmoS (Azospirillum sp. SherDot2)
MGKILVVDDERDVQTLILQRFRRAVRTGELEFLFAHDGQEALATLRARPDIDMVLSDINM
PGMDGLTLLDHLPQVNSDIRAVMVSAYGDLGNVRAAMNRGAFDFIIKPIDFADLEATIHK
TLEACQSVRRLRDALQETRTAEAASRAQAARMRRVLDGSPIGVAIITEAGDPVYCNQRCT
DLFGVPADTLQHHCAPTLFRHVQERLPNRAAGIDALSVSDEIHYVREDGRTVWMAMSVDR
TSYENQPVFIVWLYDITERKVQAEALRRAKDSAEQALADLERMQSDLIRAEKMAVIAQLI
AAVAHEINTPVGIALTAATHLQTASEGIIMTFNGGQLRKSDFQDYVGTASEVSTLLVANI
ERAAALIQSLKLVTEGKASSPRSRVGLRDYLSDIVLAVQVQPAAAGHELVLECPDGLALD
TYPGALTEVLLALLTNAFAHAFEAAPAPVGFGISESDQPEDSIRRPGQVTVSVRMMGDER
VELRVSDNGRGIPADIQPRLFQPFTTTRRGAGSMGLGLYAVFNLVTGKLGGEIDIDSEVG
RGTCVILRLPLDAP