Protein Info for MPMX19_01740 in Azospirillum sp. SherDot2

Annotation: NADH-quinone oxidoreductase chain 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 687 PF13510: Fer2_4" amino acids 4 to 76 (73 residues), 65.6 bits, see alignment E=8.7e-22 TIGR01973: NADH dehydrogenase (quinone), G subunit" amino acids 4 to 596 (593 residues), 746.8 bits, see alignment E=1.2e-228 PF00111: Fer2" amino acids 7 to 53 (47 residues), 32 bits, see alignment 2.4e-11 PF10588: NADH-G_4Fe-4S_3" amino acids 83 to 120 (38 residues), 65 bits, see alignment 9e-22 PF00384: Molybdopterin" amino acids 271 to 599 (329 residues), 343.3 bits, see alignment E=4.1e-106 PF09326: NADH_dhqG_C" amino acids 635 to 671 (37 residues), 60.4 bits, see alignment 5.3e-20

Best Hits

KEGG orthology group: K00336, NADH dehydrogenase I subunit G [EC: 1.6.5.3] (inferred from 97% identity to azl:AZL_021420)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (687 amino acids)

>MPMX19_01740 NADH-quinone oxidoreductase chain 3 (Azospirillum sp. SherDot2)
MPKLTIDGIEIEVEPGTSILQACEQLGIEIPRFCYHERLSVPANCRMCLVEMERAPKPVA
SCAMPCGDGMVVRTNSETVLKARKGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGFDR
GRYGENKRAVKDKYMGPVIKTIMTRCIHCTRCIRFINEVAGVPDVGAVYRGEHMEITTFV
EKAIGSELSGNLADVCPVGALTHKPYAFTARPWELRKTETVDVLDAVGSNIRVDARGPEV
MRVLPRVNDDINEEWLNDKSRYSYDGLKRQRLDRPYIRQNGKLVPASWAEAFTAISARLK
GLSGNRVAAIAGDLVDVEAQFALKELLSRLGSANLDCRQDGARFDTSVRAGYLFNSGIAG
IEKADVILLVGTNPRWEGTLVNARIRKRYMAGGVTIASIGEQRDLTYPYSVIGSGPDALQ
QLVDGSHPFSETLRAAKNPMIIVGMGAFQRVDGLAVQAAARLVGEAYGMFRDDWNGFNVL
HTAAARVGGIEAGFLPGEGGRDVHGILDGASKGEIDFVYLLGADEIDMAKLGNAFVVYQG
HHGDAGAHRADVILPGAAYTEKNAVYVNTEGRPQLARLAVFPPGEAREDWKIVRALSEVL
GTTLPFDTHGQLRQRLMAANPIFGAVGEMTPASWAPFGAQGPVDAAPFVTPITNFYMTDP
ISRASVTMANCTEALVGPAQERTGTHG