Protein Info for MPMX19_01737 in Azospirillum sp. SherDot2

Annotation: NADH-quinone oxidoreductase subunit J

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 51 (20 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 91 to 115 (25 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details PF00499: Oxidored_q3" amino acids 18 to 168 (151 residues), 136.6 bits, see alignment E=2.8e-44

Best Hits

Swiss-Prot: 58% identical to NUOJ_RHOCA: NADH-quinone oxidoreductase subunit J (nuoJ) from Rhodobacter capsulatus

KEGG orthology group: K00339, NADH dehydrogenase I subunit J [EC: 1.6.5.3] (inferred from 93% identity to azl:AZL_021390)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (204 amino acids)

>MPMX19_01737 NADH-quinone oxidoreductase subunit J (Azospirillum sp. SherDot2)
MILQGIAFYVFAALLVASGVMVISARNPVHSVLFLILAFFQAAGLCLLMGAEFIAMILII
VYVGAVAVLFLFVVMMLDINFRELRKGAMEALPLGALVGLILLAELAAVLGGWIVAPNVA
AIAGAPTPAFDQVSNTQALGRLMYTQYVYLFQASGIVLLIAMIGAIVLTLRHRPGVRKQN
VGAQIARRREDVVAIRKVSTGEGV