Protein Info for MPMX19_01707 in Azospirillum sp. SherDot2

Annotation: Phosphatidylserine decarboxylase proenzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 transmembrane" amino acids 20 to 52 (33 residues), see Phobius details TIGR00164: phosphatidylserine decarboxylase homolog" amino acids 11 to 219 (209 residues), 177.9 bits, see alignment E=8.2e-57 PF02666: PS_Dcarbxylase" amino acids 45 to 217 (173 residues), 145.1 bits, see alignment E=1.1e-46

Best Hits

Swiss-Prot: 65% identical to PSD_MAGSA: Phosphatidylserine decarboxylase proenzyme (psd) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K01613, phosphatidylserine decarboxylase [EC: 4.1.1.65] (inferred from 97% identity to azl:AZL_021070)

Predicted SEED Role

"Phosphatidylserine decarboxylase (EC 4.1.1.65)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 4.1.1.65)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.65

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>MPMX19_01707 Phosphatidylserine decarboxylase proenzyme (Azospirillum sp. SherDot2)
MSAIDTVVVPIHRAGWPFIAGFAVVSLILGLAVWAPLGWIGLVLTLWCAYFFRDPDRVTP
TRPGLLVSPADGRVTMIVQAVPPKELGMGDKALTRISVFLNVFNVHVNRVPADGTIVAAE
YHKGTFVNAALDKASDENERMAFRHRLPDGREIAYVQIAGLVARRILWWVKAGQQVKAGE
RFGLIRFGSRTDIYLPDGVAPLVCVGQTAIGGETILADLDGTETQRQGDVRR