Protein Info for MPMX19_01696 in Azospirillum sp. SherDot2

Annotation: S-adenosylmethionine:tRNA ribosyltransferase-isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR00113: S-adenosylmethionine:tRNA ribosyltransferase-isomerase" amino acids 1 to 336 (336 residues), 381.1 bits, see alignment E=2.2e-118 PF02547: Queuosine_synth" amino acids 4 to 336 (333 residues), 423.4 bits, see alignment E=2.8e-131

Best Hits

Swiss-Prot: 62% identical to QUEA_RHORT: S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queA) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K07568, S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC: 5.-.-.-] (inferred from 95% identity to azl:AZL_020970)

Predicted SEED Role

"S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.-.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.-.-.-

Use Curated BLAST to search for 5.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>MPMX19_01696 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Azospirillum sp. SherDot2)
MKTADFDFDLPPDRIAEHPVRPRDAARLLEVGSTLRDFIVRDLPTLVQPGDLMVVNDTRV
IPARLDGRRGEVAVEITLHKRLGEREWATFSKPGKRLKPGDTIVIADDFSAEVIAKDGME
VRLRFSAGGAELMEALHRHGRMPLPPYIRRKADEGDNADYQTVFAAREGAVAAPTAGLHF
TPELLAALDERGVRRVPVTLHVGAGTFLPVKVDDIADHKMHSEWGEISAETAAAVNETRK
AGGRIVSVGTTALRILETAGRPDGTLVPFSGDTDIFITPGYRFRIVDLLWTNFHLPKSTL
FMLVCAFAGYDRMHAAYRHAIDTDYRFFSYGDASLLHRTDPT