Protein Info for MPMX19_01246 in Azospirillum sp. SherDot2

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 39 to 63 (25 residues), see Phobius details amino acids 188 to 210 (23 residues), see Phobius details PF00672: HAMP" amino acids 208 to 259 (52 residues), 29.3 bits, see alignment 1.3e-10 PF00512: HisKA" amino acids 264 to 323 (60 residues), 46.3 bits, see alignment E=5.3e-16 PF02518: HATPase_c" amino acids 366 to 469 (104 residues), 79.4 bits, see alignment E=4.1e-26

Best Hits

KEGG orthology group: K07638, two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC: 2.7.13.3] (inferred from 91% identity to azl:AZL_013630)

Predicted SEED Role

"Osmolarity sensor protein EnvZ (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>MPMX19_01246 Adaptive-response sensory-kinase SasA (Azospirillum sp. SherDot2)
MTASGQAGADNAAAKRAAVRRAERRRRTPFLKRFLPRTLFGRSLLIIVTPVILAQAVATW
IFYDRHWDTVTNRLAYGVAGDIATVIAVLEHDPTPEGRDWTLATAARTTDLIVTLEPGQI
LPEQRRQQSGLLGGLLERTLGKALEDRVGRPFTINTRVAHEWYEIRVQMADGVLSVMSPE
RRLFTPTSYIFILWMVGSAIVLFAVAILFMRNQIRPIKRLAIAADALGKGRDVSNFKMEG
ATEVRQAASAFLLMRERIQRQINQRTEMLAGVSHDLRTPLTRMKLALDMIEDPDLDPEVE
ELKADVAEMEEMIEGYLAFARGEGTEAVQPTDLTRLLNEVAAGARREGTEVTLTAPEGLS
LPLRPNAVRRCIANLLVNAGRHAGSAWVKAEREGGTIEITVDDDGPGIPAYLRDDVFKPF
FRVDSSRNLDTGGSGLGLTIARDVARSHGGDITLDDSPYGGLRAVIRLPI