Protein Info for MPMX19_01175 in Azospirillum sp. SherDot2
Annotation: Homospermidine synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 55% identical to HSS_BLAVI: Homospermidine synthase (hss) from Blastochloris viridis
KEGG orthology group: K00808, homospermidine synthase [EC: 2.5.1.44] (inferred from 96% identity to azl:AZL_014430)MetaCyc: 55% identical to homospermidine synthase monomer (Blastochloris viridis)
Homospermidine synthase. [EC: 2.5.1.44, 2.5.1.45]; 2.5.1.44 [EC: 2.5.1.44, 2.5.1.45]; 2.5.1.44 [EC: 2.5.1.44, 2.5.1.45]
Predicted SEED Role
"Homospermidine synthase (EC 2.5.1.44)" (EC 2.5.1.44)
MetaCyc Pathways
- homospermidine biosynthesis I (1/1 steps found)
- homospermidine biosynthesis II (1/1 steps found)
- hypusine biosynthesis (1/5 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.5.1.44 or 2.5.1.45
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (473 amino acids)
>MPMX19_01175 Homospermidine synthase (Azospirillum sp. SherDot2) MALDTKLCTFTGRMVIVGFGSIGQGVLPLLLRHIDGLTADRITIVTAEERGREEAELYGV AFHNNPLDNDNFFQVLKPLIDKGDFLVNLSVDVSSLALIEFCQRVGAFYTDTCTEPWAGG YTDSSLSPSLRSNYALRESALALRGRYEGGPTALITHGANPGLVSHFVKQALLNIAADTG VETDVPTDRDGWGRLAQRLGIKTIHVAERDTQVSNQPKRIGEFVNTWSIDGFVSEGCQPA ELGWGTHEKDLPPDGRRHEFGCDAAIYLMRPGAATRVRTWTPLEGPFHGFLITHSEAISI SDYFTVRDGDRVVYRPTCHYAYHPCDDGVMSLHELAGKNYNMQAEQRLMMHEITGGMDEL GVLLMGHPKGAYWFGSRLDIDTARSLAPYNNATSMQVTSTVLGGIVWTLENPNRGLVEPD EVDFRRVLDIATPYLGEVVGAYGDWTPLQDRNVLFPEDIDEDDPWQFKNFRVN