Protein Info for MPMX19_01148 in Azospirillum sp. SherDot2

Annotation: Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 PF02541: Ppx-GppA" amino acids 57 to 324 (268 residues), 144 bits, see alignment E=6.8e-46 PF21697: Ppx_C" amino acids 364 to 508 (145 residues), 75.7 bits, see alignment E=5.4e-25

Best Hits

KEGG orthology group: K01524, exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC: 3.6.1.11 3.6.1.40] (inferred from 93% identity to azl:AZL_014810)

Predicted SEED Role

"Exopolyphosphatase (EC 3.6.1.11)" in subsystem Phosphate metabolism (EC 3.6.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.11, 3.6.1.40

Use Curated BLAST to search for 3.6.1.11 or 3.6.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>MPMX19_01148 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (Azospirillum sp. SherDot2)
MNIEKRAAANFGELGQAVGSASGVATAGERVGDRVGVIDIGSNSIRLVVYDGLTRSPLAL
FNEKVLCGLGRGVEKAGVLNPDGVAQGLAALERFATLAQGMRVGRLDVIATAAVRDARDG
AAFVDAIRRRAGLTVRVISGEEEARLSAMGVLSGTPGADGLVGDLGGGSLELVPLDRGVI
GRQVTLPLGPLRLMEVGSTKGGPAKMIDQHLESLPWLPAMKGRPFYPVGGSWRAIAKLHM
EQSGHPLHIIHHYTIPSADAREFTGLIGRQSRSSLEKMAGSRRRLDTLPLAGLVLERLLR
IAQPSKLVFSAYGLREGHLYSLLSPEGQREDPLMASAADWARRFVRMGDPALLMSWTAGL
FAGEDDNAIRLRHAACLLSDVGWADHPDYRAEHAFLRVLRYPFPALDHDERAFLALAAHA
RYAGTIDVPLTAPVRTLVSEGQGMKALVLGLALRLAHTLSGGATALLERTSLKVGDGRIV
LTLPDDGSVPSGEAVQRRIDALAKAMNLKGDVVQPLRPQAAE