Protein Info for MPMX19_01135 in Azospirillum sp. SherDot2

Annotation: putative methyltransferase YcgJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 transmembrane" amino acids 136 to 153 (18 residues), see Phobius details amino acids 176 to 190 (15 residues), see Phobius details PF13489: Methyltransf_23" amino acids 37 to 192 (156 residues), 71.1 bits, see alignment E=3.8e-23 PF01209: Ubie_methyltran" amino acids 38 to 157 (120 residues), 64.8 bits, see alignment E=3.2e-21 PF03141: Methyltransf_29" amino acids 39 to 144 (106 residues), 27.5 bits, see alignment E=4.9e-10 PF05175: MTS" amino acids 42 to 165 (124 residues), 26.7 bits, see alignment E=1.6e-09 PF13847: Methyltransf_31" amino acids 43 to 148 (106 residues), 84.9 bits, see alignment E=2e-27 PF13649: Methyltransf_25" amino acids 47 to 140 (94 residues), 90.3 bits, see alignment E=4.4e-29 PF08242: Methyltransf_12" amino acids 48 to 141 (94 residues), 67.4 bits, see alignment E=6.3e-22 PF08241: Methyltransf_11" amino acids 48 to 144 (97 residues), 93.7 bits, see alignment E=3.7e-30

Best Hits

Swiss-Prot: 36% identical to YCGJ_BACSU: Uncharacterized methyltransferase YcgJ (ycgJ) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 92% identity to azl:AZL_014650)

Predicted SEED Role

"SAM-dependent methyltransferase YafE (UbiE paralog)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>MPMX19_01135 putative methyltransferase YcgJ (Azospirillum sp. SherDot2)
MTRTHHGVVAENYGPRADAYVSSAVHAGGADLDQIELVLRGRSNARVLDLGCGGGHVSYR
AAPHVAEVVAVDLTPEMLEVVARTAAERGLSNIATRQAPAERLPFEDGRFDVVLCRFTAH
HWRDFEAGLREARRVLAPGGIAVFIDCIAPAAAVLDTHLQVVEVLRDPSHVRNYTAAEWM
AALARAGFAVRSLTPRRLRMEFPVWTARTRTPDLHAQAIRSLQRSAAAEVRTHFDITEDG
SFLLDTLTLEADPV