Protein Info for MPMX19_01114 in Azospirillum sp. SherDot2

Annotation: Regulatory protein AtoC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 466 PF00072: Response_reg" amino acids 5 to 116 (112 residues), 102.5 bits, see alignment E=4.7e-33 PF00158: Sigma54_activat" amino acids 142 to 306 (165 residues), 186.6 bits, see alignment E=9.1e-59 PF14532: Sigma54_activ_2" amino acids 143 to 311 (169 residues), 79.7 bits, see alignment E=7.7e-26 PF07728: AAA_5" amino acids 166 to 282 (117 residues), 30.8 bits, see alignment E=8.5e-11 PF00004: AAA" amino acids 166 to 296 (131 residues), 24.2 bits, see alignment E=1.2e-08 PF02954: HTH_8" amino acids 413 to 451 (39 residues), 37.2 bits, see alignment 6.1e-13

Best Hits

Swiss-Prot: 62% identical to NTRX_AZOC5: Nitrogen assimilation regulatory protein NtrX (ntrX) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K13599, two-component system, NtrC family, nitrogen regulation response regulator NtrX (inferred from 98% identity to azl:AZL_015050)

Predicted SEED Role

"Nitrogen regulation protein NtrX"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (466 amino acids)

>MPMX19_01114 Regulatory protein AtoC (Azospirillum sp. SherDot2)
MAHDILIVDDEADIRMLIAGILNDEGIKTREAADADQAFAQVAARRPSLVVLDIWLQGSR
LDGLQILEQLMRDHANLPVIMISGHGNIETAVQAIKVGAYDFIEKPFKADRLLLMVDRAI
EAARLKRENQELKLRAGGDAELIGKSSAVNQVRQSIDKVAPTGSRVLISGPPGAGKEVVA
RLIHARSRRAGGPFVGLNCATMRPERLEMELFGTEAGVDGPGRKIGTFEQAHGGTLLLDE
VADMPLETQGKIVRALQEQVFERVGGGQRVEVDVRVIATSNRDLQAEIEQGRFRQDLFYR
LSVVPIRVPSLAERREDIPVLARHFMQRSAEASGLPTREFGEDAMAALQAYDWPGNVRQL
RNVVDWLLIMAHGDPKESIRADTLPPEIGAITPTVLKWDKGGEIMGLPLREAREVFEREY
LLAQVTRFGGNISRTASFVGMERSALHRKLKSLGVHGSEKGKMFLE