Protein Info for MPMX19_01061 in Azospirillum sp. SherDot2

Annotation: Glutathione-regulated potassium-efflux system protein KefC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 50 to 72 (23 residues), see Phobius details amino acids 84 to 108 (25 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 146 to 168 (23 residues), see Phobius details amino acids 179 to 201 (23 residues), see Phobius details amino acids 213 to 233 (21 residues), see Phobius details amino acids 236 to 251 (16 residues), see Phobius details amino acids 267 to 288 (22 residues), see Phobius details amino acids 294 to 317 (24 residues), see Phobius details amino acids 328 to 351 (24 residues), see Phobius details amino acids 356 to 375 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 11 to 373 (363 residues), 182.4 bits, see alignment E=1.3e-57 TIGR00932: transporter, monovalent cation:proton antiporter-2 (CPA2) family" amino acids 12 to 282 (271 residues), 264.1 bits, see alignment E=8e-83 PF02254: TrkA_N" amino acids 403 to 517 (115 residues), 86.4 bits, see alignment E=1.9e-28

Best Hits

KEGG orthology group: K11747, glutathione-regulated potassium-efflux system protein KefB (inferred from 94% identity to azl:AZL_015560)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system protein KefB" in subsystem Glutathione-regulated potassium-efflux system and associated functions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (603 amino acids)

>MPMX19_01061 Glutathione-regulated potassium-efflux system protein KefC (Azospirillum sp. SherDot2)
MAELVTLVVLLAAMVVAVPVAKRFGFGAPLGYLAAGLAVGPAGLGLVTNVGAIAHASELG
VVMLLFLIGLELRPARLWVMRKSVLGLGGAQVAVTGAVIAALCGWGLGLAWPTAVVLGFG
FALSSTAMALPMMAERGLLANQSGRNAFSILLFQDLAIIPAVALLPLLGNGSVPHADGAW
LAVAKAVVAVALVLIGGRYLLRPIFHAVDRAGAPEIFTATALLIVIGTAVLIQEAGLSMS
LGAFMAGVLLSDSEYRHEVQADIEPFEGLLLGLFFVSVGMGADVPTLMAHPIRFLGLAVA
LLVVKGAVLLVLARIAGVPWAGAGRMATVLSQGGEFGFVLFGLAVGGGAMAGEQASAAML
VVTLSMLATPFLFAAEERWFAPRLMAGKPKRPFDTPPDENPPVIICGFGRVGQVVGRVLR
MRGIAFTALESSAAQVDFVRKFGSKAYYGDPTRVELLRAAGAEKASVLVVALDDMEQSLR
VVEMATRHFPNLTIFARARNRRHVHHLMDRGVTHIVRETLDSSIRLTGDVLRQMGMAEGE
VVRTLDTFRAHDERTLIRQHAVHNDETKLIQTSRDAAAELQSLFEADREDAVQGEAEPRT
ASA