Protein Info for MPMX19_01001 in Azospirillum sp. SherDot2

Annotation: UDP-2,3-diacylglucosamine pyrophosphatase LpxI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF17930: LpxI_N" amino acids 16 to 145 (130 residues), 127.5 bits, see alignment E=3.2e-41 PF06230: LpxI_C" amino acids 150 to 279 (130 residues), 158.4 bits, see alignment E=8.5e-51

Best Hits

KEGG orthology group: K09949, hypothetical protein (inferred from 90% identity to azl:AZL_016140)

Predicted SEED Role

"Protein of unknown function DUF1009 clustered with KDO2-Lipid A biosynthesis genes" in subsystem KDO2-Lipid A biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>MPMX19_01001 UDP-2,3-diacylglucosamine pyrophosphatase LpxI (Azospirillum sp. SherDot2)
MADTTQSAGLPATGPKLAILAGGGTLPARIAEAVRGQGREVFIVAFDGHTDPQTVAGLPH
LWSRFGAAGTILRRLHEEGVGEVVLAGPVRRPSFTELMPDWRTARFLARVGTRALGDDGL
LRAVVREVEEDGFRVVGLHELLRDLLTVAGPVGRLMPDADAERDIARGVEVARALGALDV
GQGAVVQQGIVLAVEAIEGTDAMLGRCAGLIRPGPGGVLVKVKKPKQDRRIDLPTMGVTT
VERAAASGLRGIAVEAGGSLLVDRAAVAEAADRLGLFVVGIEIPQ