Protein Info for MPMX19_00736 in Azospirillum sp. SherDot2

Annotation: Riboflavin biosynthesis protein RibD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF00383: dCMP_cyt_deam_1" amino acids 9 to 109 (101 residues), 62.4 bits, see alignment E=4.8e-21 TIGR00326: riboflavin biosynthesis protein RibD" amino acids 14 to 367 (354 residues), 335.8 bits, see alignment E=3.1e-104 PF14437: MafB19-deam" amino acids 31 to 149 (119 residues), 47.8 bits, see alignment E=2.1e-16 TIGR00227: riboflavin-specific deaminase C-terminal domain" amino acids 156 to 368 (213 residues), 177 bits, see alignment E=3.9e-56 PF01872: RibD_C" amino acids 157 to 364 (208 residues), 163.7 bits, see alignment E=7.2e-52

Best Hits

KEGG orthology group: K11752, diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC: 1.1.1.193 3.5.4.26] (inferred from 88% identity to azl:AZL_010180)

Predicted SEED Role

"Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)" in subsystem Riboflavin, FMN and FAD metabolism (EC 1.1.1.193, EC 3.5.4.26)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.193 or 3.5.4.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>MPMX19_00736 Riboflavin biosynthesis protein RibD (Azospirillum sp. SherDot2)
MPALSDIDTDLRHMRAALSLAARGLGRTWPNPAVGCVLVRDGAVIGRGWTQPGGRPHAEA
EALARASTLSGGAEGATAYVTLEPCNHYGKTPPCALALVEAKVARVVVACQDPDPRVAGG
GLTRLRDAGIAVTTGVCEAEALTLNEGFFNRITLGRPLITCKVASTLDGRIATATGESQW
ITGPTARAWGHRLRASHDAILVGIGTALADDPELSCRLPGLEDRSPVRVVVDSSLRLPPT
AKLATGARHIPTWVVTGPTPDPVRAEALTALGVEPIPVAAGPDGRVDPAAAMTALATRGI
TRVLVEGGASMAGALLGAGLVDRLEWFRAASLIGGDGLPAVAGFGVEALAAMARFERTAI
RSAGADLAESYRRKASAASI