Protein Info for MPMX19_00657 in Azospirillum sp. SherDot2

Annotation: Response regulator protein TmoT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 PF00072: Response_reg" amino acids 5 to 113 (109 residues), 95.2 bits, see alignment E=4.3e-31 PF00196: GerE" amino acids 139 to 193 (55 residues), 71.4 bits, see alignment E=5.7e-24

Best Hits

Swiss-Prot: 50% identical to DCTR_RHOCA: C4-dicarboxylate transport transcriptional regulatory protein DctR (dctR) from Rhodobacter capsulatus

KEGG orthology group: K11712, two-component system, LuxR family, response regulator DctR (inferred from 95% identity to azl:AZL_009430)

Predicted SEED Role

"Transcriptional regulatory protein fixJ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>MPMX19_00657 Response regulator protein TmoT (Azospirillum sp. SherDot2)
MTTLHIVDDDEAIRDALGWLFQSRNVPVAGWPSAESFLESWRPDTAGCLLLDIRMEGMSG
LELFDRLLSKGCRMPVIFLTGHGDVPIAVGALKKGARDFVEKPFNDNELVDRVIDALAFD
AEQREREAGQAGLTARLATLTQRERQVMELVVAGRLNKVIADELGISMRTVEVHRSHVFE
KMRVKTAVELTRLLTGAA