Protein Info for MPMX19_00538 in Azospirillum sp. SherDot2

Annotation: GTP 3',8-cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 TIGR02666: molybdenum cofactor biosynthesis protein A" amino acids 17 to 346 (330 residues), 366.7 bits, see alignment E=5e-114 PF04055: Radical_SAM" amino acids 30 to 192 (163 residues), 117.6 bits, see alignment E=1e-37 PF13353: Fer4_12" amino acids 34 to 126 (93 residues), 30.3 bits, see alignment E=7.3e-11 PF06463: Mob_synth_C" amino acids 199 to 325 (127 residues), 126.4 bits, see alignment E=1e-40

Best Hits

Swiss-Prot: 67% identical to MOAA_RHOPT: GTP 3',8-cyclase (moaA) from Rhodopseudomonas palustris (strain TIE-1)

KEGG orthology group: K03639, molybdenum cofactor biosynthesis protein (inferred from 95% identity to azl:AZL_007210)

Predicted SEED Role

"Molybdenum cofactor biosynthesis protein MoaA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>MPMX19_00538 GTP 3',8-cyclase (Azospirillum sp. SherDot2)
MTNPVSEALPSAAVAPLVDPFGRKVEYLRVSVTDRCDLRCVYCMAEDMSFLPKAEVLTLE
ELDRLCSAFVKLGTRKLRLTGGEPLVRRDVMRLIHSLGRHIKSGDLDELTLTTNGTMLFK
HAAGLFDAGVRRINVSLDTLDPHKFQAITRWGKLDKILGGIQAAKEAGLKIKINTVALKG
VNDDEIHRMVAWCGEQGFDLTFIEVMPMGDIGEGARLDQYWPLTMLKAELQTRWTLTESD
HRTGGPARYVRVEETGQRVGFITPLTHNFCESCNRVRLTCTGTLYMCLGQEDAADLRTPL
RVSDEDGPLIDAVREAITRKPKGHDFIIDRRHQGPAVGRHMSVTGG