Protein Info for MPMX19_00425 in Azospirillum sp. SherDot2

Annotation: 7-cyano-7-deazaguanine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 TIGR00364: queuosine biosynthesis protein QueC" amino acids 10 to 221 (212 residues), 212.2 bits, see alignment E=2.9e-67 PF06508: QueC" amino acids 10 to 228 (219 residues), 261.5 bits, see alignment E=5.2e-82 PF00733: Asn_synthase" amino acids 12 to 66 (55 residues), 31.9 bits, see alignment E=1.1e-11

Best Hits

Swiss-Prot: 75% identical to QUEC_RHORT: 7-cyano-7-deazaguanine synthase (queC) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K06920, queuosine biosynthesis protein QueC (inferred from 92% identity to azl:AZL_006140)

Predicted SEED Role

"Queuosine Biosynthesis QueC ATPase" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>MPMX19_00425 7-cyano-7-deazaguanine synthase (Azospirillum sp. SherDot2)
MADRNGVRDAVVLVSGGLDSTTVLAIAKAEGYRVNALSFRYGQRHAVELEAARRVVAAMG
VERHVIADIDLRAFGGSALTDSIAVPKHDSSADLQAGLGEGIPVTYVPARNTVFLSFALA
WAETLGASDLFIGVNALDYSGYPDCRPEYIAAFETLANLATKAGVEGTSRFKIHAPLMTL
DKAAIVRRGLELGVDYSLTHSCYDPTPEGLSCGACDSCLLRLKGFSEAGMTDPIRYDAGM
KA