Protein Info for MPMX19_00249 in Azospirillum sp. SherDot2

Annotation: Chaperone protein HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 626 PF13589: HATPase_c_3" amino acids 31 to 155 (125 residues), 36 bits, see alignment E=6.8e-13 PF00183: HSP90" amino acids 216 to 625 (410 residues), 397.4 bits, see alignment E=1.3e-122

Best Hits

Swiss-Prot: 63% identical to HTPG_MAGSA: Chaperone protein HtpG (htpG) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 96% identity to azl:AZL_003810)

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (626 amino acids)

>MPMX19_00249 Chaperone protein HtpG (Azospirillum sp. SherDot2)
MTEERLSFQAEVSRLLDIVAHSLYSEKEVFLRELVSNASDACDRLRYAALTQPELSADDP
NLKIRLLVDKDARTLTVADNGIGMNRDDLVENLGTIARSGTAAFMKSLDGAEKGDGKKDV
NLIGQFGVGFYSAFMAADKVTVLTRKAGEPTGWRWESDGKGEFTVAEADGLPRGTQIVLH
LRAGDDEYLDEARLGGIVRKYSDHIAIPILFGEGDEAKALNSASALWTRSKSEITADQYK
EFYHHVGHAFDDPWLTLHWRAEGALEYTNLLYVPSTKPFDLFDPKRAHRVKLYVKRVFIT
DAAEGLIPPYLRFLRGVVDSEDLPLNISREMLQHNPMLAKIKAGITRRVLSELSKKAKDS
ENAAEYDSFWENFGAVLKEGLYEDYEHRDELLKLLRFRTTAGDELVSLEQYVARMKDGQD
AIFTISGDDIDTLLRSPQLEGFKAKGVEVLLLTDPVDEFWMPSVGVYDGKPFKSVTRGGA
DLGKIKGEEAEKPEEKTPEGELTDLLALLKLTLSDAVKDVRKSERLTDSAVCLVADDNDM
DMHLERLLKQHKQLNGEVGKRILEINPSHALIKRLADRAKGSGATDALEDAAWLLLDQAR
IVEGEPLPDPAAFARRLASAMEKGLA