Protein Info for MPMX19_00239 in Azospirillum sp. SherDot2

Annotation: putative adenylyltransferase/sulfurtransferase MoeZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 52% identical to TTUC_THET2: Sulfur carrier protein adenylyltransferase (ttuC) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

KEGG orthology group: None (inferred from 96% identity to azl:AZL_003700)

MetaCyc: 52% identical to [sulfur carrier protein TtuB] adenylyltransferase (Thermus thermophilus)
2.7.7.M15 [EC: 2.7.7.M15]

Predicted SEED Role

"Sulfur carrier protein adenylyltransferase ThiF" in subsystem Thiamin biosynthesis

MetaCyc Pathways

superpathway of thiamine diphosphate biosynthesis II (10/11 steps found)
thiazole component of thiamine diphosphate biosynthesis II (6/7 steps found)
superpathway of thiamine diphosphate biosynthesis I (8/10 steps found)
thiazole component of thiamine diphosphate biosynthesis I (4/6 steps found)
tRNA-uridine 2-thiolation (thermophilic bacteria) (2/5 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.M15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>MPMX19_00239 putative adenylyltransferase/sulfurtransferase MoeZ (Azospirillum sp. SherDot2)
MLRAMDFTDTQLHRYSRHIVLPEVGGIGQEKLLRSKVLVVGAGGLGAPLLLYLAAAGVGT
IGIVDDDTVDLSNLQRQVIHDESTLGLAKVESAAARIHALNPDVRVEAHRTRINRDNAMD
LIAGYDLVADGSDNFATRFLLNDACFLAGKTLVSAAILRFDGQLTTFKAHLGAPHPCYRC
LFPEPPPRGTVPSCSEGGVLGALAGSVGSLQATEVLKELLGLGESLSGSLLMMDTLYASY
QRIAIKRDPDCALCGDHRTIHDLSAH