Protein Info for MPMX19_00206 in Azospirillum sp. SherDot2
Annotation: Cytochrome c oxidase subunit 1, bacteroid
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 68% identical to FIXN_BRADU: Cytochrome c oxidase subunit 1 homolog, bacteroid (fixN) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 99% identity to azl:AZL_003350)MetaCyc: 65% identical to cytochrome cbb3 oxidase subunit I (Rhodobacter capsulatus)
CYTOCHROME-C-OXIDASE-RXN [EC: 7.1.1.9]
Predicted SEED Role
"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)
MetaCyc Pathways
- arsenite to oxygen electron transfer (2/2 steps found)
- aerobic respiration I (cytochrome c) (3/4 steps found)
- arsenite to oxygen electron transfer (via azurin) (2/3 steps found)
- NADPH to cytochrome c oxidase via plastocyanin (thylakoid membrane) (2/4 steps found)
- aerobic respiration II (cytochrome c) (yeast) (2/4 steps found)
- succinate to chytochrome c oxidase via cytochrome c6 (thylakoid membrane) (1/3 steps found)
- succinate to cytochrome c oxidase via plastocyanin (thylakoid membrane) (1/3 steps found)
- Fe(II) oxidation (2/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.9.3.1
Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (498 amino acids)
>MPMX19_00206 Cytochrome c oxidase subunit 1, bacteroid (Azospirillum sp. SherDot2) MTSATLTSGATLGSQRVSEDVRYHEDAIRLFVIAAVFWGVVGFLAGTFIALQLAFPALNL GLEWTSFGRLRPVHTSAVIFAFGGNVLFATSLYSVQRTCRQYLFGGEGLAKFIFWNYNVF IVLAALSYVLGFTQGKEYAEPEWILDLYLTVTWVLYAVQFIGTVMTRRESHIYVANWFFM AFILTVAILHIGNNINIPVSLFGMKSYTFVSGVQSAMVQWWYGHNAVGFFLTAGFLGIMY YFVPKRAERPVYSYRLSIVHFWTLIFLYIWAGPHHLHYTSLPDWAQTLGMTFSVMLWMPS WGGMINGIMTLSGAWDKLRTDPVLRFLVTSVAFYGMSTFEGPLMSVKPVNALSHYTDWTI GHVHSGALGWVAFVSFGAIYYLVPVLWKRSQLYSMRLVSYHFWTATIGIVLYITAMWVSG IMQGLMWRAYDNLGFLQYSFVETVAAMHPFYVIRAMGGVLFVTGALIMVYNLWRTAKGDV RIEKPYVTTPHKATVGAA