Protein Info for MPMX19_00118 in Azospirillum sp. SherDot2

Annotation: putative parvulin-type peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 signal peptide" amino acids 1 to 55 (55 residues), see Phobius details PF13145: Rotamase_2" amino acids 171 to 295 (125 residues), 69.1 bits, see alignment E=9.4e-23 PF13616: Rotamase_3" amino acids 184 to 283 (100 residues), 96.2 bits, see alignment E=2.9e-31 PF00639: Rotamase" amino acids 202 to 281 (80 residues), 87.1 bits, see alignment E=2e-28

Best Hits

KEGG orthology group: K03769, peptidyl-prolyl cis-trans isomerase C [EC: 5.2.1.8] (inferred from 89% identity to azl:AZL_025620)

Predicted SEED Role

"Foldase protein PrsA precursor (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (352 amino acids)

>MPMX19_00118 putative parvulin-type peptidyl-prolyl cis-trans isomerase (Azospirillum sp. SherDot2)
MAPMPQTMRNGRRPIGRPFVKHPPEGNRHAMVQRVFRTALLSVAACGIALAAHAQTPAPA
TPAPAAPAPAAAAAPPPAAPADPVVARVNGEELHKSDVTRMVSQLPPQVQQMPIEMIYPA
VIDQLVSGKLVSSAGYKAGLADSAEVKDEIKRAEERAVQRAYIQKEIKARVTPEALNKAY
QDYLKENPAQEEVKAAHILVEKEDEAKAIIAQLKKGGDFAKLAKEKSKDAAAAAQGGDLG
YFTKDAMVEPFANAAFAMKPGEISKEPVKTQFGYHIIKVEDKRTQPQPTLDEVKPQLEQT
LSKDMVTALVEELRGKAKVETFQLDGSPMPKEEPAAAPATPAPAAPAEPAKK