Protein Info for MPMX19_00117 in Azospirillum sp. SherDot2

Annotation: Protein translocase subunit SecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 911 PF07517: SecA_DEAD" amino acids 7 to 388 (382 residues), 434.7 bits, see alignment E=3.9e-134 TIGR00963: preprotein translocase, SecA subunit" amino acids 28 to 808 (781 residues), 1117.7 bits, see alignment E=0 PF01043: SecA_PP_bind" amino acids 232 to 345 (114 residues), 134.4 bits, see alignment E=6.4e-43 PF21090: P-loop_SecA" amino acids 404 to 608 (205 residues), 318.9 bits, see alignment E=3.3e-99 PF07516: SecA_SW" amino acids 610 to 822 (213 residues), 240.3 bits, see alignment E=5e-75 PF02810: SEC-C" amino acids 891 to 909 (19 residues), 37.3 bits, see alignment (E = 5.1e-13)

Best Hits

Swiss-Prot: 68% identical to SECA_BRUO2: Protein translocase subunit SecA (secA) from Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)

KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 96% identity to azl:AZL_025630)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (911 amino acids)

>MPMX19_00117 Protein translocase subunit SecA (Azospirillum sp. SherDot2)
MFGALARKIFGTANTRAVKALHKTVAQINALEPSVAALSDDQLKGRTDWLRERLAKGETL
DDILPDAFATVREAAKRVLGQRHFDVQLMGGMVLHSGKIAEMRTGEGKTLVATLAVYLNA
LEGKGVHVVTVNDYLASRDSGWMARVYGFLGLSTGCIVHGLDDDERRAAYAADITYGTNN
EFGFDYLRDNMKFRLEELVQRPFNFAIVDEVDSILIDEARTPLIISGPSTDSSEMYVQVD
RLIPMLVAEDYEKDEKHRTVSFTEAGQEHMEQLLAEAGLLKTGGLYDIQNVALVHHSQQA
LRAHMLFQRDKDYIVKDDKVVIIDEFTGRMMDGRRFSEGLHQALEAKEKVTIQRENQTLA
SITFQNYFRIYPKLAGMTGTALTEAAEFGEIYGLEVVDMPTNVPVKRIDHDDEVYRTATE
KYHAMTDLIEDARKRGQPVLVGTTSIEKSELLSELLTKRGIPHNVLNARHHEQEAYIVAQ
AGRAGAVTVATNMAGRGTDIQLGGNLQMRIEVELADIPEGPERDARIQQIEAEIAEAREK
VKQAGGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSKFFLSLEDDLMRIFGSERMDSML
QRLGLKEGEAIIHPWINKALEKAQQKVEAHHFEVRKNLLKFDNVMNDQRKVVYEQRHEVM
ESEDIAEEIREMRHQIIANMVSTAIPANSYSEQWDIDGLHEAVNRVLGMDLPVQEWAKEE
GIAEPEIEERVREAADRKYADKEEAYGAETMRHVEKSILLQILDQEWKDHLLQLDHLRQG
INLRAYAQKDPLNEYKREAFELFDSMLMALREQVTTILMHVEIRMAPSQEELFARQMQEM
HEGRMDPALAMAGDAEALPDGMVRASSLASSLVGTPEDQPLPAEVMENTPRNAACPCGSG
KKFKHCHGRMA