Protein Info for MIT1002_04053 in Alteromonas macleodii MIT1002

Annotation: putative DMT superfamily transporter inner membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 32 to 51 (20 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details amino acids 146 to 168 (23 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 213 to 232 (20 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details amino acids 268 to 286 (19 residues), see Phobius details PF00892: EamA" amino acids 6 to 135 (130 residues), 48.4 bits, see alignment E=5.4e-17 amino acids 151 to 284 (134 residues), 59.6 bits, see alignment E=1.9e-20

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_04029)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (300 amino acids)

>MIT1002_04053 putative DMT superfamily transporter inner membrane protein (Alteromonas macleodii MIT1002)
MNNATLFALCCLIWGSTWIAITYQIGHTSETFAIALRYLLASACLGIYCVIRRLPLKLPV
HVHVKMAAVGLFLYSLNYTLLYMAQAHIISALLALMSSCIIYINVVLRRWWLKEPIRKEV
VIGATFGLLGIVCLFVPEFSKVSMDAALATGLAIAFVSFFCASTGNVISERILTSGTPVI
QMNFYAMSYAMVLLFITSLAMPGKLVIPTQPEFYLSLLYLAIFGSVFAFGAYMKLLKQMG
ADKAAYVVLVYPMVALVISTFFEGYTWSVLSVVGVVIVLVGNAIAMGKIPRFMRRPPVSS