Protein Info for MIT1002_04023 in Alteromonas macleodii MIT1002

Annotation: DNA-damage-inducible protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 50 to 72 (23 residues), see Phobius details amino acids 96 to 124 (29 residues), see Phobius details amino acids 144 to 162 (19 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details amino acids 277 to 299 (23 residues), see Phobius details amino acids 320 to 344 (25 residues), see Phobius details amino acids 357 to 378 (22 residues), see Phobius details amino acids 388 to 407 (20 residues), see Phobius details amino acids 413 to 435 (23 residues), see Phobius details PF01554: MatE" amino acids 24 to 185 (162 residues), 55.2 bits, see alignment E=3.6e-19 amino acids 248 to 405 (158 residues), 52.4 bits, see alignment E=2.6e-18 TIGR00797: MATE efflux family protein" amino acids 24 to 416 (393 residues), 245.9 bits, see alignment E=3.5e-77

Best Hits

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 92% identity to amc:MADE_04000)

Predicted SEED Role

"DNA-damage-inducible protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>MIT1002_04023 DNA-damage-inducible protein F (Alteromonas macleodii MIT1002)
MSPAQPTQRSFFDDHSRLLALALPMILANITTPLLGLVDTAVLGHMSLPAMLAGASVGAL
ILTQIYWVCGFLRMSSTGLSAQAKGSPNNTLESAKVLWQTVAVALVLGAVVLALQSPILS
IGLALTQPNSEVALHLQDYFSTRVWGAPAAMLNLALVGWLVGQQKTRSVMAIQIVGNLLN
AGLDVVFVFGLGLSVAGVALASVIAEYTMAIMALAVAFKRVGGVAVSASWFNRAARKVLM
KLNGDMLLRNLALQGCLAFLTIQGARYGETSAAVNAILMQFFVLIALGLDGIAYGVEALV
GEAKGASDSSEVKRRTYQGLVWSSIFALIYSLIFFAGGEAIIALLTEHSDIVKAALPYLD
LMVLLPLLAHWCFLYDGVFVGLTRASAMRNTMIISALGVYFPVWYLTQDQGNVSLWYALL
AFLLARGMTLAWSFYRLDKRGELATPQS