Protein Info for MIT1002_04019 in Alteromonas macleodii MIT1002

Annotation: Fe/S biogenesis protein NfuA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 TIGR03341: IscR-regulated protein YhgI" amino acids 2 to 192 (191 residues), 328 bits, see alignment E=8.7e-103 PF01521: Fe-S_biosyn" amino acids 2 to 98 (97 residues), 47.7 bits, see alignment E=1.7e-16 PF01106: NifU" amino acids 111 to 173 (63 residues), 62.5 bits, see alignment E=3.3e-21

Best Hits

Swiss-Prot: 96% identical to NFUA_ALTMD: Fe/S biogenesis protein NfuA (nfuA) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K07400, Fe/S biogenesis protein NfuA (inferred from 96% identity to amc:MADE_03996)

MetaCyc: 77% identical to iron-sulfur cluster carrier protein NfuA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"NfuA Fe-S protein maturation"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (192 amino acids)

>MIT1002_04019 Fe/S biogenesis protein NfuA (Alteromonas macleodii MIT1002)
MITISEEAQAHFVKLLSKQESGTNIRVFVVNPGTSSAECGVSYCPPDAVEETDTRLPFNG
FDAVVDEESAPYLEEAEIDYVTDQMGSQLTLKAPNAKARKVSDDAPLIERINYMIESEIN
PQLASHGGNVVLTELTDDGYAILQFGGGCNGCSMVDVTLKEGIEKQMVEQFAGELKGVRD
ATEHQAGEHSYY