Protein Info for MIT1002_03977 in Alteromonas macleodii MIT1002

Annotation: Type II traffic warden ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 TIGR02533: type II secretion system protein E" amino acids 36 to 518 (483 residues), 731.8 bits, see alignment E=1.8e-224 PF00437: T2SSE" amino acids 147 to 413 (267 residues), 376.3 bits, see alignment E=3.7e-117

Best Hits

Swiss-Prot: 76% identical to GSPE_AERHY: Type II secretion system protein E (exeE) from Aeromonas hydrophila

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 97% identity to amc:MADE_03957)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>MIT1002_03977 Type II traffic warden ATPase (Alteromonas macleodii MIT1002)
MAGQDEQITQALEAQEEALEAMGEDAGLPEEEAGPRQLSFSFAKRNQVLLETNETPAVLY
FTENTPFDVFAEVRRFYGEPFVPKTIPANEFESLLTSAFQRDSSAAKQLMEDLGNESDLF
ALAEDLPDTEDLLDSEDDAPIIKLINAMLGEAIKEGASDIHIETFENQLVVRFRVDGVLR
EILRPNRKLSSMLVSRIKVMAKLDIAEKRVPQDGRITLRIAGRAVDVRVSTMPSSHGERV
VLRLLDKNNARLNLEDLGMTLQNRNHFSSLIRKPHGIILVTGPTGSGKSTTLYAGLTEIN
SRDRNILTVEDPIEFDLPGIGQTQVNPRVDMTFARGLRAILRQDPDVVMVGEIRDIETAQ
IAVQASLTGHLVLSTLHTNTAAGAITRLEDMGIEPFLLSSSLLAVLSQRLVRTLCPDCKK
PHSPDASELEILGQNATSDATIYKPHGCAACNQTGYRGRTGIHELLLVDEKVREMMHEGV
GEQAIERYIRKTTPSIREDGCSKVLAGATSLEEVLRVTRED