Protein Info for MIT1002_03928 in Alteromonas macleodii MIT1002

Annotation: Ubiquinol oxidase subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 105 to 129 (25 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 191 to 215 (25 residues), see Phobius details amino acids 235 to 256 (22 residues), see Phobius details amino acids 289 to 307 (19 residues), see Phobius details amino acids 318 to 337 (20 residues), see Phobius details amino acids 348 to 370 (23 residues), see Phobius details amino acids 379 to 405 (27 residues), see Phobius details amino acids 418 to 442 (25 residues), see Phobius details amino acids 457 to 479 (23 residues), see Phobius details amino acids 495 to 517 (23 residues), see Phobius details amino acids 601 to 628 (28 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 4 to 649 (646 residues), 1124.4 bits, see alignment E=0 PF00115: COX1" amino acids 58 to 506 (449 residues), 482.2 bits, see alignment E=7.6e-149

Best Hits

Swiss-Prot: 72% identical to CYOB_PSEAE: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 99% identity to amc:MADE_03911)

MetaCyc: 70% identical to cytochrome bo terminal oxidase subunit I (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (662 amino acids)

>MIT1002_03928 Ubiquinol oxidase subunit 1 (Alteromonas macleodii MIT1002)
MSLLGKLSIEAVPYHEPIIMVTLAVVAVVGVVIAMLITKHKQWGTLWFDWITSVDHKRLG
IMYIVLAMIMLLRGFADAIMMRTQLAMATNGAPGYLPPEHYDQIFTAHGVIMIIFMAMPF
MIGLMNIILPLQIGARDVAFPFLNNLSFWLTAGGAILVNVSLGLGEFAKTGWVAYPPLAG
LEFSPGVGVDYYIWALQISGLGTLLTAVNFLVTVFKMRAPGMKLMQMPIFTWTCTWANIL
IAASFPILTAVLAMLTLDRYMDFHFFTNEAGGNSMMYINLFWAWGHPEVYILVLPAFGIF
SEVISTFTAKRLFGYKSMVYASGAIAILGFIVWLHHFFTMGSSANVNAFFGIMTMVIAVP
TGVKLFNWLFTMYRGRLILSVPVLWTLGFMVTFTIGGMTGVLLAIPGADYVLHNSLFLIA
HFHNTIIGGAVFGYLAGFAFWFPKAMGFKLDEKTGKAAFWCWQIGFLLAFMPLYVLGFLG
MTRRLNHTDNPDWNIWLYIAAFGAFVIAIGIFFQLLQLFVSFKNKENLNDTTGDPWNGHT
LEWSTASPPQFYNFAKIPHIKDIDAWTDMKERGESYQRPEKYTPIHMPKNTSAGVFMSMS
FTLMGFALIWHIWWLAVVGLVAGIGVFIKRCYTSDVDYYVQVDEVERVEATHLSANTVGG
RS