Protein Info for MIT1002_03858 in Alteromonas macleodii MIT1002

Annotation: putative TonB-dependent receptor precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 28 to 103 (76 residues), 58.2 bits, see alignment E=2.3e-19 PF13715: CarbopepD_reg_2" amino acids 29 to 110 (82 residues), 48.9 bits, see alignment E=1.4e-16 PF07715: Plug" amino acids 122 to 227 (106 residues), 77.5 bits, see alignment E=2.7e-25 PF00593: TonB_dep_Rec" amino acids 322 to 771 (450 residues), 95.3 bits, see alignment E=2e-30

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 64% identity to pat:Patl_0295)

Predicted SEED Role

"Zinc-regulated outer membrane receptor" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (802 amino acids)

>MIT1002_03858 putative TonB-dependent receptor precursor (Alteromonas macleodii MIT1002)
MKLSRLALGLSLSAPALLLASPAALAQTLSGTVTNAAGKPLANATVEIEALKRVTSTNEL
GEFTFSNVKEGDYTLHIFASGFAHLHEHAQVQSDNAEGANFVLARSAIEVIDVHATPMHL
SVMESATPVSVLSGETLRRQQAATLGDTLEKLPGVQSNFHGNVASTPIIRGLSGPRVLIT
QNGLDVSDVSRVGPDHAVASEASTAKQIEVLRGPATLFFGSGAIGGVVNVVDQRVPTSTE
TRGEFVLETQTVNDQKLGTFNVTTGVDNIAFYADGFYRDSNDYETPVAPDIDDPDGAHVV
ENSNEESNGFTLGTSYLFDQGYVGVAVERFEREYGVPGHSHGGDTSVFADLEQTKYQLLG
EYNFTNDFLQSVHFRAGYTDYEHAEVEGGLVGTTFSNETEELRVELLHKPMAGWRGGISL
HYKGSDVFAQGEEAFTPPSEMEMFAVALMEERHFGDFLVQLGARAESVTLDASSVLLPEL
DAHEHNDEHDHDEHAHDEHEHEGSEFVRQFAVDQEFTPISLSAGVVYTISESYNVGVSLS
RSERAPSASELLSFGPHIGTRTYEIGALFDLSEEGEFVLSQTAIDLETANNIDLTFRKTQ
GDVGFVFNAFYNQVDNYYFQEETGLFAESGHDHDHGEEGHGEEEHSEDEHSDELPVYLFG
SADAILHGFELQVAWQTTDNLKLDFFADYVKARLKDGGALPRTSPMRVGSHVAYTLDNIR
ADLDITYFAKQDDISTFETETDGYTLVDASITYDIPLGDIDLSVYLSGENLTDEEARVHT
SFLKDIAPRPGRNFAFGVRGYF