Protein Info for MIT1002_03702 in Alteromonas macleodii MIT1002

Annotation: Signal transduction histidine-protein kinase BaeS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 411 to 431 (21 residues), see Phobius details TIGR03785: proteobacterial dedicated sortase system histidine kinase" amino acids 2 to 708 (707 residues), 922.3 bits, see alignment E=9.3e-282 PF00512: HisKA" amino acids 489 to 551 (63 residues), 43.4 bits, see alignment E=2.8e-15 PF02518: HATPase_c" amino acids 600 to 710 (111 residues), 44.9 bits, see alignment E=1.5e-15

Best Hits

KEGG orthology group: None (inferred from 86% identity to amc:MADE_03558)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>MIT1002_03702 Signal transduction histidine-protein kinase BaeS (Alteromonas macleodii MIT1002)
MVLSLFLFTIPYLGYNYVWELEQYLRNGQEQTMIGTARAVATALHERPALFDSQSAYLQD
VRPGTDLYAPPIPSPIRLDGELNDWQQVSELMSEYGSGEVIEYYNGYAGEPTSLSFKHMV
GRYGQFLYAMFEVSDDVLLWRQPNSLSVETGDHLLVGMETPQGELARYVVAPYESGWVNA
YKLAENTTTTRAVENALSIQGRWQETATGYNIELRFPLSMTTGGLAFSIVDVDDRASRLK
QYALGTANTKELAELGTVITPSPEIERILAGLKYADSRVWVVDKHKRVLARAGDIQSATG
IEVDEKETSSNTIWHWVESEWLLPLYYQILTRPPADFIDELDDAYALVGQDLGTALNGQP
DSLWRLSPDNKAIVLSAAYPIFIEGNVMGAVIVEQTTNGIRTLRNRALEQLFHVILAVMT
IGTLGLLLFATRISNRIRSLRDNTEAVIDDNGKIIGTLPVSNQRDEIGDLSRSFADVLSR
LQQYNSYLENMASRLSHELRTPIAVVKSSLDMLTQVNDADQQAVFVERAQSGVNRLSTIL
NSMSEATRLEQAIQQEDLEPFDLVKVISGCIAGYEHAYSHRRFSFTHNADTARILGSPEL
TAQMFDKVIANAVDFSEKESEIQVSITVKDKQAELTISNTGPLLPEGMRSQLLQSMVSVR
KENDVQNASSPHLGLGLYIANIIMTFHKGQLSLFNRKDSTGVVVSARFPLM