Protein Info for MIT1002_03622 in Alteromonas macleodii MIT1002

Annotation: Cytochrome d ubiquinol oxidase subunit 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 13 to 39 (27 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 86 to 104 (19 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details amino acids 150 to 176 (27 residues), see Phobius details amino acids 188 to 211 (24 residues), see Phobius details amino acids 224 to 246 (23 residues), see Phobius details amino acids 258 to 282 (25 residues), see Phobius details amino acids 302 to 324 (23 residues), see Phobius details PF02322: Cyt_bd_oxida_II" amino acids 12 to 325 (314 residues), 267.9 bits, see alignment E=6.3e-84

Best Hits

KEGG orthology group: K00426, cytochrome bd-I oxidase subunit II [EC: 1.10.3.-] (inferred from 96% identity to amc:MADE_03484)

Predicted SEED Role

"Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases (EC 1.10.3.-)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>MIT1002_03622 Cytochrome d ubiquinol oxidase subunit 2 (Alteromonas macleodii MIT1002)
MFENVSAEMLGNIYVGLLGLSVLLYAILDGYDLGVGVLIPPRTEAFRDDMIASIGPYWDA
NETWLVLAIGLLLIAFPEAHSEFLQTLYLPATFMLLGLIMRGVAFDFRAKVVQVKKRKWD
MVFKYGSLLTTLAQGYMLGIYVTGLRTDIWAQGFALLAAFGVTAAYAFIGSCWLILKGEG
ELQQKAYYWARRGLGVLAVGIVAVSIANLTLHDDVRDLWLSAPWGYVLFAIPVACFALLA
LCGVLLKKLPDAQGKGEWLPFFIALLVFLLCFTAFGISYYPFIIPGQMTVMDALSDASSL
RFLLVGVVIVVPIILAYTAMVYKIFSGKSEKLSYY