Protein Info for MIT1002_03552 in Alteromonas macleodii MIT1002

Annotation: Alpha-hemolysin translocation ATP-binding protein HlyB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 139 to 157 (19 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 246 to 271 (26 residues), see Phobius details amino acids 278 to 296 (19 residues), see Phobius details PF00664: ABC_membrane" amino acids 27 to 294 (268 residues), 50.7 bits, see alignment E=1e-17

Best Hits

KEGG orthology group: K02021, putative ABC transport system ATP-binding protein (inferred from 92% identity to amc:MADE_00632)

Predicted SEED Role

"Toxin secretion ABC transporter ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (575 amino acids)

>MIT1002_03552 Alpha-hemolysin translocation ATP-binding protein HlyB (Alteromonas macleodii MIT1002)
MAKPIDLRKTRKTLFSLLKPEAGFFWVAIAYGVAISLMTLAVPIAVQTLINSIANIGSTR
AVIILAVILFLTLFISGVFSALRMRVMEFYERKVYARLTADLGLKTILAPHSFFEGRQNV
SITQRYFDIMTFQKNMPSLMIDGFALVLQMLVGFTLVSFYHPALFAFNVVLLLTMYAVWK
IWGRGAKRTAIELSNAKYDSAKWLHDIAIAHEFFKSADHVEYAGRSTEGYISNYVKKHKS
HFHYTFSQVVMFLLMYAVASASLLGIGGVLVVQGELSIGQLVAAELVMSAVFFGLSRFTQ
YLKLYYELYGAAEKLGGALDMPQEELNTSEHIPASSKLVFNDVELKHGNDACHLNVIFEP
GTKYFVTTDKSWVQKQLLGLLKQYDRVKSGDILLGELSLNDYDTHELRQAVTILDRSLII
EVSVERYLKLAHPQATIADIRAALEEVEMTKVIDSLPEGLQTKVSVLGAPLQPLEFLLLK
LAAAIIGKPKLLILNQHFDAIPVELRARLLRHLSKYDFTVMYFTNMPLPDCFEGVLHLHD
NATAMLNEYSNGESPISAANASESSTASKNNKEGE