Protein Info for MIT1002_03526 in Alteromonas macleodii MIT1002

Annotation: Nitrogen regulation protein C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 PF00072: Response_reg" amino acids 5 to 117 (113 residues), 90.2 bits, see alignment E=1.6e-29 PF00196: GerE" amino acids 146 to 202 (57 residues), 62.9 bits, see alignment E=2.6e-21

Best Hits

Swiss-Prot: 42% identical to NREC_STAES: Oxygen regulatory protein NreC (nreC) from Staphylococcus epidermidis (strain ATCC 12228)

KEGG orthology group: K07696, two-component system, NarL family, response regulator NreC (inferred from 38% identity to bts:Btus_0609)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (209 amino acids)

>MIT1002_03526 Nitrogen regulation protein C (Alteromonas macleodii MIT1002)
MTIRVVLADDHVLMRQGVSQMLNANPDISVVGECDDGVALIAAVLKLSPDVILMDISMPR
MSGLVAIDKILSQRSDAKILVLSMHNEVEYIEAMRDAGAKGYILKESSGESLIEAIKKVA
ANKTCFPDELTQSSSDQCQKHVSPLSVLTRREREVFFLVAAGNTSKKIAELLNMSLKTAE
NHRSNIYKKLNLSSSAELIRMAGKAGLLE