Protein Info for MIT1002_03506 in Alteromonas macleodii MIT1002

Annotation: Arabinose 5-phosphate isomerase KdsD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 PF00571: CBS" amino acids 153 to 201 (49 residues), 37.3 bits, see alignment 4.1e-13 amino acids 212 to 267 (56 residues), 43.6 bits, see alignment 4.7e-15 PF03445: DUF294" amino acids 295 to 428 (134 residues), 121.6 bits, see alignment E=3.5e-39 PF10335: DUF294_C" amino acids 465 to 604 (140 residues), 120.6 bits, see alignment E=7.3e-39

Best Hits

KEGG orthology group: K07182, CBS domain-containing protein (inferred from 85% identity to amc:MADE_00722)

Predicted SEED Role

"Predicted signal-transduction protein containing cAMP-binding and CBS domains" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (609 amino acids)

>MIT1002_03506 Arabinose 5-phosphate isomerase KdsD (Alteromonas macleodii MIT1002)
MTAMAKQVEDFLNTSAPFELLDNDQKHALVKHTELIYLTNENVNDVFKDKVSLFLIQSGQ
FSVKDSDAPTRHLSDGDYFGYTNIIEKSNFPLSITVDSPGLVYCFDALAIEPLLEIPVIR
HFFDGLRNNALQNHAIADSNSMWLYKGLTDAIEKAPVSVDAQTPITVAAQLMTSQKVSSL
LVTQEEKLIGIITDRDLRSRVVAASLDIHLPVSQIMTANPAQIMGNRTLFDALALMTEKN
IHHLPVIDNQTQVPLGMVTASDIIRHQRGNVLFIIGELSKAENLYELTRLSWQLPHYFSA
HAKKAGDYDIAGKILSQATDIMTRKLIGFFQQANGKAPMMFAWLVYGSQAREDQTMGSDQ
DNGLLLAERPSEAQAEYFAKMADYVCNGLAKCGIKLCDGNIMASNPKLRLSLEEAIEEAK
RWVKAPTKDAIMHFNIFLDVRCAAGDISLFKQLQRQRAPLMKQNMFLAALTRNSNEISVP
LSMFQKFIYEKGRKEKDVIDLKTRAVALINNIARIYALADGVTLPNTLARLDALSENSQL
SKSDATNLRDIWLFLNRLRWHHQLENKVTDNRVSVSSLSSIEKHQLKAAFKAIERTNQAM
VMKFSGGVS