Protein Info for MIT1002_03495 in Alteromonas macleodii MIT1002

Annotation: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1008 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 33 to 109 (77 residues), 51.6 bits, see alignment 1e-17

Best Hits

KEGG orthology group: None (inferred from 81% identity to alt:ambt_00380)

Predicted SEED Role

"Oar-like outer membrane protein protein, OmpA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1008 amino acids)

>MIT1002_03495 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein (Alteromonas macleodii MIT1002)
MRTSAKFSRIAAAVALSIGLSSTAMAQVTSSELNGKIMGPQGNPAAGTVVTVTHVPTGAV
KTVTVNSGGTFSLRGLRVGGPYTVVIDSDEFADQTINDVYLELGESASIERMLEPAAQYE
NIVVTGSQISSLSFGQTGPVASFDLSTLEEAPAINRDITDIVRIDPRIYVDEGGSNGIQC
VGKSPRFNSLTVDGVRMNDLFGLNSNGYPTERMPFSFDAIAGVSVEIAPFDVIYGGFSAC
NISAVSKTGTNEVHGSAFYDFGSDSLRGDSLEGDDINLGAYTEKRYGFTVGAPLIKDKLF
IFAAYEKLEGANTFDRGAIGSGAINEVNITQAEVERIQQISQNIYNFDAGSVPSSLANED
EKLLVKLDWNINDQHRLAFTYNYNDGNNFAQSDGDADEFEFSSHLYERGAELQSFIGVLY
SDWTDKFTTEIRIARTELDNLQRSFYGDGTPGGNDFGEIIIRMANDPENSADDLDVYLGS
DDSRQANDLDWDATSIMFRGNYYFDNGHTLTFGYENDKLDIFNLFVQHAETTTTFNSIDD
FENGANARIEYGYAYSGNLLDRAAEWGYTSHSTYAQDEFYLTDDLKVVAGLRYDWITTSD
RPLENTDFTESYGYSNSANLDGVDLLQPRVGLNYTLSDSTELRGGFGLFSGGNPNVWMTN
NYQNTNVTGGEVRNDYANILDGSITWVNTEDGVTAGPGYSVPSDLDATMDSGVGRNFEPN
NLDPDFVMPSEWKISAGMTHVTDEDYVFNLDLLVSITQDQAMIKYKGIEAVGVTEDGYVD
YERNGLGSLELTNSNESSTSYSLTATMNKSWDNGISIVGGYNYSHAEDVQPMTSSVAFSN
FQYRAFHDPNEEVSSLSDWNIAHRFTLDFRYTTQFFDGLDTTFSAFAVAQSGKPYSFTLS
RSDSQAAYGTPYLDSNNVLPIGAERNDEESPWWAKVDIAVRQDVPAFHQDHTAQVFFVID
NFTNMLNDDWGILEETSFNTAVVGSSNPERRQGDASLWEMRVGVNYRF