Protein Info for MIT1002_03402 in Alteromonas macleodii MIT1002

Annotation: Type IV secretory pathway, VirB4 components

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 PF01935: DUF87" amino acids 143 to 404 (262 residues), 96.3 bits, see alignment E=4.5e-31 PF10412: TrwB_AAD_bind" amino acids 163 to 205 (43 residues), 24.1 bits, see alignment 2.5e-09

Best Hits

KEGG orthology group: K06915, (no description) (inferred from 76% identity to nit:NAL212_1050)

Predicted SEED Role

"Bipolar DNA helicase HerA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (576 amino acids)

>MIT1002_03402 Type IV secretory pathway, VirB4 components (Alteromonas macleodii MIT1002)
MTIFNFNDEEALGKVASVDTATVVVEVYDAELLKRLQVNRLAVLQSSKPGQHLIGIINQV
TRKKLIPSAIEEDEDPSDEQNLCKVALIGSLIDADGIKRNIFRRTLESVPEIDANCFALE
GEKLTSFMRVISHAEADGNSLTLGKYTLDENAVAYLNGNKFFQRHAFIGGSTGAGKSWTT
ARIIEQVSQLKNSNAIIFDLHGEYSPLKGDGISHFKVAGPSDIESNRTLADGAIYLPYWL
LSYEALVSLFVDRSDQNAPNQAMLMAREVNSAKTKYLEEGGYQDILDNFTVDSPVPFDLT
SLIHELNAINVERIPGARAGSDKAGEFNGKLSRMISRLENKISDRRLGFLFQGGADVLEF
DWLNRLADALLGSNDENGNGGVKIINFSEVPSDVLPLIVSLVARLAFSVQQWTPSEERHP
VAILCDEAHLYIPNKNVSGVSDDISIQIFERIAKEGRKYGVSLVVVTQRPSEVNKTILSQ
CSNFVAMRLTNSDDQSVIKKLLPDSLGGFSDILPTLDTGEALVVGDASLLPSRIRIDEPN
NKPDSGTIDFWKEWQGDVTAGRLNKAIDNWRKQNIQ