Protein Info for MIT1002_03376 in Alteromonas macleodii MIT1002

Annotation: Bacteriophytochrome cph2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 741 PF11849: DUF3369" amino acids 153 to 321 (169 residues), 172.4 bits, see alignment E=1.5e-54 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 322 to 472 (151 residues), 50.3 bits, see alignment E=1.1e-17 PF00990: GGDEF" amino acids 325 to 469 (145 residues), 63.2 bits, see alignment E=3.8e-21 PF00563: EAL" amino acids 493 to 727 (235 residues), 228 bits, see alignment E=1.7e-71

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_03585)

Predicted SEED Role

"Response regulator/GGDEF/EAL domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (741 amino acids)

>MIT1002_03376 Bacteriophytochrome cph2 (Alteromonas macleodii MIT1002)
MSAMDYDNDELIFLDDDGSVEEQTLLGKDWNILIVDDDEEIHTVTRLALSDLIVNDRKLN
FIHAYSAKQAKEMLHEYGNSIAIILLDVVMETDDAGFDVVKYIREDMKLVEPRIILRTGQ
PGYAPEEQVIKVYDINDYKTKTELTRAKLLTTIISSLRSYQQIVTISQSRAGLEKIITSS
ANLFEEHSVKEFCEGVVTQISSLIGLDSEGLLCARAGSLLDREDEEVYVLGAAGEYAKFI
NQPVFTLKNLEIEENISRCLRLKKHIFEPSCSVLYISRAGFEAAVFVRQTHEISELDKHL
LEVFLSSISVGYENVNLFHELRNAAFRDWLTRLPNRNEFINMLDKPHLFAGENYSVALID
VNHFSDINDGLGQEVGNELLRAISDRFQSSFDSIVKKGRIGADVFGLIGPDDLVCPKSIN
NIFQSSFQVGDHTLPVNITLGLCKLDNKRHIGIEILKRTNIALNRAKKNLTDNFEYYAKD
IEDQTTWRLDMIRQLRSDFAARKLELWFQPQVDLLNEKVVGMEGLLRWPNGEGGYVSPAV
FVPLAEYSGLIVDIGEWVLEESCRRLQELKEKGYGHLRVAVNISIPQFRDRLFVEKVKQA
LSNANCDPSLLELEITESVVMDEPQIVIDALRSLKEFGVKIAIDDFGTGFSSMSYLQQLP
LDRLKVDRSFVKDIKPGASAVLAETVVTLGNKLGLLTIAEGVEKREQASYMIKLGCDEAQ
GYLYAKPMPFDALLAFLEEHD