Protein Info for MIT1002_03372 in Alteromonas macleodii MIT1002

Annotation: Fatty acid desaturase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 36 to 58 (23 residues), see Phobius details amino acids 70 to 91 (22 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 179 to 205 (27 residues), see Phobius details PF00487: FA_desaturase" amino acids 39 to 260 (222 residues), 94.8 bits, see alignment E=4e-31

Best Hits

KEGG orthology group: K00507, stearoyl-CoA desaturase (delta-9 desaturase) [EC: 1.14.19.1] (inferred from 97% identity to amc:MADE_03581)

Predicted SEED Role

"Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)" (EC 1.14.19.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.19.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>MIT1002_03372 Fatty acid desaturase (Alteromonas macleodii MIT1002)
MKKPPLILTNVLVFIISGAIAFIGVPLWVAYQGIDWAEIGAAIFLFYFTGMSITAGYHRL
WSHKTYDANVVVRVILAVGGAMALQNSILHWSSDHRVHHRHVDDNDKDPYSAKKGLWFAH
IGWMLREYQAKRYDDYSNCKDLQKDKVVMWQHNYYLPIVLAANFGITGLLGYLNGDVLGM
ILVAGVLRLVLVHHVTFFINSLAHFWGSQPYTDKNTARDNGILAFFTFGEGYHNYHHIFE
YDYRNGIRWYQFDPTKWLIKGLSLVGLTSNLRKVPEERIEKALAAMQLQRASEKVSLLPN
AEEMMHTIQEEYDLLMQRMSEYYATKKRVMRVKQRTLKRSIEGLELAYKYKELKHAFAVQ
KEKWTQLHSLSLQMA