Protein Info for MIT1002_03318 in Alteromonas macleodii MIT1002

Annotation: Sensor protein EvgS precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 837 TIGR00229: PAS domain S-box protein" amino acids 321 to 443 (123 residues), 29.8 bits, see alignment E=2.8e-11 PF08448: PAS_4" amino acids 331 to 438 (108 residues), 59.6 bits, see alignment E=1.2e-19 PF00512: HisKA" amino acids 475 to 539 (65 residues), 36.8 bits, see alignment 1.2e-12 PF02518: HATPase_c" amino acids 584 to 692 (109 residues), 73.1 bits, see alignment E=8.8e-24 PF00072: Response_reg" amino acids 723 to 831 (109 residues), 41.7 bits, see alignment E=4.2e-14

Best Hits

KEGG orthology group: None (inferred from 73% identity to alt:ambt_01115)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (837 amino acids)

>MIT1002_03318 Sensor protein EvgS precursor (Alteromonas macleodii MIT1002)
MQPNNQFTDVEALQKALYEQRRENEKLEKINAALMYRMEEGGFNHHSYRAFEHSVQLSEK
VSQKTEELQSVLQKLEQSNAELVRAHEETHQVKQRLHDAIESTNQAMVLLDRLGGIIFFN
RHFETVWDDLSITPKIGDNYYDITQAAKHSGVIRRALPADVEGRMIYQLSNRRWYQLTNR
PTQEGGNVILFNDITEVKLLESNRYEQVIKEKNKLLQSLIDNIDVGILLIDKEGGIAFWN
NTFLTQSNVPQHVLVNSKNIYALQNNRHWSGLNLKPVGPSTQIIHEQLVVERNITTLPDG
NTLCTFTNVTSQHHYAETLKQNESWIRMITDNVPALIAYIGTDKKFQYTNKGYRDWYGVS
EQDINDMPMDRSHLKEVYPNLIQYLRRVNQGEVVSFQSKEKNAHGDVGFLQKVYLPHFNE
SGDITGHFVLATDVSQQVESQLQLKAAKDQLESNVEKRTRELNHANIALQEAIDSKSKFL
AAISHDLMQPLSAAILFNETLKDQVDSSSSPIVTALDNSLSDLHGLIRTLIETSKLDAGV
LQPDKQQENVLPLLMQLAEEFTHISKDYSVDFRYRLKEAFVVTDVNLLSRILRNLLINAM
KYGANGKVLLAARKVNENLEISIYDQGVGISEDDQKVIFKEFSSLENDFNYSYSLGLGLY
IVDKMSKLLEHDIRVRSKEGVGACFTVTIPITEVCDTSQEQDYLYTLEPSLPDYVLDKHI
WHIDNDANMRIAMQTLFANWDMEVDTFSGFEQCSAVNNGSFDECDMLIVDYHLDEEETGL
DIAKRVRKIAPSMPIMICTANHSKALANELEGTDIQLLHKPVNSSVLKAALVSSLNG