Protein Info for MIT1002_03303 in Alteromonas macleodii MIT1002

Annotation: Negative regulator of allantoin and glyoxylate utilization operons

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 PF09339: HTH_IclR" amino acids 10 to 60 (51 residues), 38.4 bits, see alignment 1.3e-13 PF01614: IclR" amino acids 128 to 246 (119 residues), 111.4 bits, see alignment E=4.4e-36

Best Hits

KEGG orthology group: None (inferred from 31% identity to gth:Geoth_1715)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (257 amino acids)

>MIT1002_03303 Negative regulator of allantoin and glyoxylate utilization operons (Alteromonas macleodii MIT1002)
MATERYTIPSVVHACEILRLMANSEQGLSMQALEEALSLPRTTVFRLLKTLLAENLLEKR
GKLYFSGASLLQLGLQVIHSDRLQHFAIPHIQRLALQTGYTAHLAVPNHGKALIVEVFDS
PSPLMVSKRPGGEAQLHCSATGKVFLAFLYADNVELLMEEHPMEKHTDLTITEIDVLEKE
LSRVRAMGYAVDEREYNKDIRCVAVPVRDSMGTVVAALGITAPAAVFPKGNIQQVSDLVK
EAARGIYKDTYQLDRAK