Protein Info for MIT1002_03298 in Alteromonas macleodii MIT1002

Annotation: xylose isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02629: L-rhamnose catabolism isomerase
  • amino acids 10 to 420 (411 residues), 659.6 bits, E=9.3e-203
• PF01261: AP_endonuc_2
  • amino acids 100 to 291 (192 residues), 41.2 bits, E=8.1e-15

Best Hits

Swiss-Prot: 63% identical to RHAL_RHIME: Probable sugar isomerase R00627 (R00627) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 64% identity to mpc:Mar181_0461)

Predicted SEED Role

"L-rhamnose isomerase (EC 5.3.1.14)" in subsystem L-rhamnose utilization (EC 5.3.1.14)

MetaCyc Pathways

• L-rhamnose degradation I (5/5 steps found)
• superpathway of fucose and rhamnose degradation (8/12 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.14

Protein Sequence (431 amino acids)

>MIT1002_03298 xylose isomerase (Alteromonas macleodii MIT1002)
MLKRIDQTLLEKENVTLKRDLEADYAALGEKLARSDVDIERLTCAAGEFQIAVPSWGTGT
GGTRFARFPGEGEPRNIWEKLEDCAVINELSGCTDSVSPHFPWDKVSDFSELKEKADEYG
IKWVSVNSNTFQDQVGQTASYKYGSLSNTQKASRELAIAHNLDCIEYGRKLGAKSLTVWV
GDGSNHPGQQHFQRAFERYLSSMEEIYKGLPDDWEIHIEHKMFEPAFYSTIIQDWGSNIL
AAMQLGPKCKSLVDLGHHAPNTNIEMIVSRLIQFKKLGGFHFNDSKYGDDDLDSGSLHPY
QQFLIFNELVDAEYRQQEEFGPAYMLDQSHNVTDPAESLINSAIEVQRSYVKALIVDREK
LYGYQDENDALMASLELKNAFNLDVSPILAMARLRKGAAIDPLAVYRKSNYRENMAKARP
RDPNATGSGIV