Protein Info for MIT1002_03290 in Alteromonas macleodii MIT1002

Annotation: Insulinase (Peptidase family M16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 PF00675: Peptidase_M16" amino acids 30 to 125 (96 residues), 29 bits, see alignment E=4.7e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (578 amino acids)

>MIT1002_03290 Insulinase (Peptidase family M16) (Alteromonas macleodii MIT1002)
MSEFHFIDAGSGSKVHSVVFALKTPAAGHTGLSHLAEHMSFRRSHQYPAAHELFTANTLL
PVTINATTLAEYTFFFASSEKANVLLDAVNYLYCGLLNRDYGTDEVILERDGVIFNELAM
LETNSDYALNAAIRLTDTNKNAYQHAGGFTQTIGSNSIQALQDYKRQWYQPSNITTLVYS
NSAHFFEQCKEVVTAVSEEIALSAQTALSAMKAQSVETALSAEKTLSEESTLNRNASLSQ
HASQREHSHLDKEASLDAQTTKGENESIRHVLTWWFPQCFLNGLLQQEATLSTVAGLENT
LFIDPEINQQGNFAIRLVTNEAMKEVASELSIEALPKLSQNLTHKLVSDDNDKRLRQLKH
VVSACLASFDIRPSKPMPDTDKHAEGVGAAIRYFAQLTDALGSNECAAKDCATKSTYLAS
ANKVSHSYLRALPSPEKSVARERIRKARKDFSAQASASNSEQSLLIPHLNSKYRHFIALE
HLPALPRLLRPLANKTTNLKRFNAEHIASHWVYRIAFYQQSRLQAVLAHHLFWQPRTSGE
CYALGAATYENNLFLFGASDTNITERENWCHKVLSMLS