Protein Info for MIT1002_03194 in Alteromonas macleodii MIT1002

Annotation: Signal transduction histidine-protein kinase BarA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 892 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 289 to 310 (22 residues), see Phobius details PF00672: HAMP" amino acids 307 to 347 (41 residues), 23.5 bits, see alignment 1.1e-08 PF00512: HisKA" amino acids 393 to 457 (65 residues), 66.3 bits, see alignment 4.1e-22 PF02518: HATPase_c" amino acids 504 to 620 (117 residues), 92.1 bits, see alignment E=6.2e-30 PF00072: Response_reg" amino acids 771 to 882 (112 residues), 94.5 bits, see alignment E=9.2e-31

Best Hits

KEGG orthology group: None (inferred from 82% identity to amc:MADE_01579)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (892 amino acids)

>MIT1002_03194 Signal transduction histidine-protein kinase BarA (Alteromonas macleodii MIT1002)
MLSSIRIQLITVLLALIALILAQGFIARENQEVLNKGVASASKAAVDVALVKELERDVVD
LQRNVLIFKENASKSAITRFSRLMVTINNKLDKLALVDEDNEEQEGNHILSRMKGHLNAY
QENFTQVVDARSERDNLIARGTLSDITLLEKILSDAKANGDISAASEEQAKSLLIRAESA
MLKYLMKPDMGFIRAFNEATDSLRKLTLTKNTSLQERVERLSENIKADFVKLTQITQGNL
FLVNVVMAGSANEFLYLSGELAKKVTTDSEIATQRTYTLAESTQRNGELFSLVSILLALS
AALFTMFRILGPIRSITQVFNKLAQGVQISNIPGSSRKDEIGKLAKAALVFSDKNRETEK
LLGEARTMNSQLESLNKAITEAKIKAEQATASKSMFLANMSHEIRTPMNGIIGLIELAQQ
QELSTTVKGYLDKAAYSGQILLSVINDILDFSKIEAGKLKIEEVSFSLHSLFDNLIAVIA
LRAKEKNLSVHFTVNPKIPPQVIGDPLRIAQTIMNIGNNAVKFTEQGRIDIEFDGNLNEK
GNVLNLTMRITDSGIGMSAAQLDRIFNPFTQADGSTNRKYGGTGLGLAIVSQLTELMNGR
LDATSTMGKGSTFEVELPLKAFKNQPGVLEQTPQLPVDSLYVTEVALLPAAYCNQIQLPT
KSTLSIEEAKNIAALPEHIIVDIHEFSEFRQNIAWLNALLEKGKSVGLVMESAGSALQAK
YDTLWRGPLIMHPFTPAQFERFVHQVISKDASYDGHHFSEEAEATSLEGHVLLVEDNNIN
QLVTGEMLTNLGLTFDIAEDGKQAVQKVENAPQYDLILMDVQMPVMDGYEATKQLREKGF
TGVPIIGLSANAMKEDKQSAIDAGMNDYLTKPIKQKSLIGMLKQYLGKQRYV