Protein Info for MIT1002_03187 in Alteromonas macleodii MIT1002

Annotation: Chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 PF01627: Hpt" amino acids 13 to 105 (93 residues), 32 bits, see alignment E=1.8e-11 PF13487: HD_5" amino acids 199 to 354 (156 residues), 93.8 bits, see alignment E=1.6e-30 PF01966: HD" amino acids 216 to 330 (115 residues), 45.3 bits, see alignment E=1.5e-15

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_01587)

Predicted SEED Role

"Metal-dependent phosphohydrolase, HD subdomain:Hpt"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (379 amino acids)

>MIT1002_03187 Chemotaxis protein CheA (Alteromonas macleodii MIT1002)
MQTFTPDDLEEDILADLMEEINELYESSEQTLIELELRPEDNELQRALFRSIHTIKGDLG
LVNFSPMIPLLQHVEDLLDYLRKGQVAYTSTMSDLVLLTMDRVKAFVEAVMASGKAEYDD
NLHNQLVLAIGRVTPENTAEHEKRLTEAVLLLNPALDIVADEDDPQNVQIKPPTLAATGI
PKDISSEKKQDILFFRDLMQTIERRSNYWSGRGDRIAKLAMYINDVAENPIDEDQLAVAS
YVHDFGMAFMPLKLLHKGDALSDIEFNLMRSHVYKSARLLEHLDQWDMARKIVMQHHERT
DGTGYPLGLKEDDICEGAKLLAIVDTYDAMTHPRAHNEDNVLSKKEAVIEINRSAKGQFS
MKWVRHFNQGMTALLTKGH