Protein Info for MIT1002_03114 in Alteromonas macleodii MIT1002

Annotation: Lipoprotein activator of PBP from the outer membrane A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF04348: LppC" amino acids 66 to 379 (314 residues), 101.8 bits, see alignment E=2.3e-33 amino acids 404 to 650 (247 residues), 146.7 bits, see alignment E=5.6e-47

Best Hits

KEGG orthology group: K07121, (no description) (inferred from 82% identity to amc:MADE_03355)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (666 amino acids)

>MIT1002_03114 Lipoprotein activator of PBP from the outer membrane A (Alteromonas macleodii MIT1002)
MRHIGQAGKIFTLSAVASVLVLTGCGSTPKTQSKPVVVEPTPIETTQVEDNVTPEHKLLE
AKKVWERTRNKEQRDTLLLQAADLYLQNQQPVLAQQVLYEVKEDGISGVNQSYYSLLVTK
AYAGMPDASAEELLAMLDGITGTGETAFQKAELQTQLFTQQGNLAAAANSVLKTNLTDDE
KVQQVWQWITSIPASSLDSVGSAYPDLSPFITLRELTEENASSPEKLAKSLQQFKQVYRG
HVLENALPENVIEATQLTDAGANDIAVLLPLSGRLARTGQVVKNGIMAAYYTDVEKRQDE
HLLPRLRFIDTNEVDTQHLLSEIGDTKFIIGPLLKDTVERLIPSLPLGVNVLALNRPDEL
PDNASAKGLATGSSNPAIADDALASGTGLAGDDTQNELHSLGLPTSLNYYGLAPEDEAKQ
LAEFIFNKGYRAPIVIAAQSSLYQRMDDTFKKHWRILNNQENKQRANITSVSFNDSNSLR
EGITQALDVAQSNQRINQIEYMTNDEVYNMPRSRRDIDAIVAFASPQDTELLNPIIEASL
NPYDGKQVPVYATSRSMDYDSGKNQWRDLQNVHFIDMPWLMPSHSWQPLQQEVEQAWQNQ
NTMQKRLFAFGFDAYQLLPQLGMLNTLKYLSHEGLTGTLSLNQQGEVIRKQPQAIIRNEK
VQMLSE