Protein Info for MIT1002_03094 in Alteromonas macleodii MIT1002

Annotation: arsenical-resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 38 to 55 (18 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 224 to 245 (22 residues), see Phobius details amino acids 251 to 272 (22 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 312 to 334 (23 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 1 to 334 (334 residues), 423.4 bits, see alignment E=3.4e-131 PF13593: SBF_like" amino acids 14 to 320 (307 residues), 39.1 bits, see alignment E=5.7e-14 PF01758: SBF" amino acids 47 to 246 (200 residues), 147.8 bits, see alignment E=3e-47

Best Hits

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 92% identity to amc:MADE_03336)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>MIT1002_03094 arsenical-resistance protein (Alteromonas macleodii MIT1002)
MGFFERYLSVWVGLCIVAGVGLGYAMPGVFASIAALEYAHVNLIVAVLIWLMIYPMMVQI
DFGSIKDVGKKPKGLVLTLVINWLIKPFTMALLGWLFFKGIFADWVDPQTATEYIAGMIL
LGVAPCTAMVFVWSHLTKGDANYTLVQVSINDLIMVVAFAPLTAMLLGVTDITVPWDTLL
LSVALYVVLPLVAGYITRRHLENKGNNAQGNGAVDALVSKFKPFSVIGLLLTIVILFGLQ
AETILSQPQDIVLIAIPLLIQTYGIFAIAYFAAKRMKLPHNVAAPACMIGTSNFFELAVA
VAISLFGLHSGAALATVVGVLVEVPVMLSLVWFANKTRHWFD