Protein Info for MIT1002_03080 in Alteromonas macleodii MIT1002

Annotation: Transaldolase B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 TIGR00874: transaldolase" amino acids 3 to 317 (315 residues), 519.5 bits, see alignment E=1.7e-160 PF00923: TAL_FSA" amino acids 14 to 312 (299 residues), 338.2 bits, see alignment E=2.1e-105

Best Hits

Swiss-Prot: 97% identical to TAL_ALTMD: Transaldolase (tal) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K00616, transaldolase [EC: 2.2.1.2] (inferred from 97% identity to amc:MADE_03321)

MetaCyc: 70% identical to transaldolase B (Escherichia coli K-12 substr. MG1655)
Transaldolase. [EC: 2.2.1.2]

Predicted SEED Role

"Transaldolase (EC 2.2.1.2)" in subsystem Folate Biosynthesis or Fructose utilization or Pentose phosphate pathway (EC 2.2.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>MIT1002_03080 Transaldolase B (Alteromonas macleodii MIT1002)
MSNQLASLRDITTVVADTGDIDAIKKYQPVDATTNPSLLLKAAGLPQYASLIDDAVAWAK
LQSNDADQQLTDAADKLAVAIGKEISATIPGRISTEVDARLSFDTAATIEKAERLVQLYE
DAGIDKSRILIKIASTWEGIQAAEELEKKGIQCNLTLLFSFAQAQACAEAGVYLISPFVG
RILDWYKKATGTESYAPDEDPGVVSVTKIYNYYKDHGYNTVVMGASFRNIGEIQALAGCD
RLTISPALLEELANEPGDLEVKLKDNGATKTPGDRLTESEFRWAMNEDAMATEKLSEGIR
NFAADQEKLETMLREKLSA