Protein Info for MIT1002_03037 in Alteromonas macleodii MIT1002
Annotation: Membrane dipeptidase (Peptidase family M19)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 87% identity to alt:ambt_02150)Predicted SEED Role
"Zn-dependent dipeptidase"
MetaCyc Pathways
- leukotriene biosynthesis (2/6 steps found)
- gliotoxin biosynthesis (2/9 steps found)
- peptido-conjugates in tissue regeneration biosynthesis (6/17 steps found)
- arachidonate metabolites biosynthesis (3/74 steps found)
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.4.13.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (404 amino acids)
>MIT1002_03037 Membrane dipeptidase (Peptidase family M19) (Alteromonas macleodii MIT1002) MKGRFPLSSCALLISALFASHSILAETSTYSASEKAIKIAQETIIVDGHIDVPYRVKEKW VDVTKATQDGDFDYPRAVSGGLNAPFMSIYVPASLDNSPESTQLAHELIDSVEAIAARAP DKFAIAKSPSDVKAQFEKGLISLPMGMENGSPIQGDLANLTAFYERGIRYITLAHSQANH ISDSSYDLRRKWKGLSPFGKTLVGEMNNIGIMLDISHVSDDAFYQVIELTKVPVIASHSS LRRFTPGFERNMDDEMIKKLGENGGVIMINFGSSFVSKEAGKWRSGLTAARKALVEKEGE DSPKLENFEENYRKEVPYPYSTLDEVLDHIDHVVKLIGVDHVGIGSDYDGVGDSLPIGLK DVASFPNLVQGLLDRGYSRTDIEKILSGNLLRVWQQVEDYAAAH