Protein Info for MIT1002_03026 in Alteromonas macleodii MIT1002

Annotation: Cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 transmembrane" amino acids 28 to 49 (22 residues), see Phobius details amino acids 62 to 84 (23 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 121 to 147 (27 residues), see Phobius details amino acids 159 to 176 (18 residues), see Phobius details amino acids 181 to 198 (18 residues), see Phobius details amino acids 204 to 221 (18 residues), see Phobius details amino acids 281 to 306 (26 residues), see Phobius details amino acids 326 to 348 (23 residues), see Phobius details amino acids 358 to 377 (20 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 28 to 382 (355 residues), 422.6 bits, see alignment E=6.5e-131 PF01098: FTSW_RODA_SPOVE" amino acids 30 to 382 (353 residues), 374.4 bits, see alignment E=2.7e-116

Best Hits

Swiss-Prot: 80% identical to FTSW_ALTNA: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Alteromonas naphthalenivorans

KEGG orthology group: K03588, cell division protein FtsW (inferred from 89% identity to amc:MADE_03259)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (474 amino acids)

>MIT1002_03026 Cell division protein FtsW (Alteromonas macleodii MIT1002)
MIAASTKLSALFAAKHDGQPSATHPYDVTLILIALALMSIGIIIVTSASMPVADRLHDNP
FYFAIRHGIYIVGAIVAAMVVLNLPMQFWRMTNPYLLLAAIALLLAVLVVGRTVNGSTRW
LAIGPITIQAAEPAKLFFFAYLAGYLVRRYEEVTENLKGFIKPLVVFFALAMLLLLQPDL
GTVVVMFATTIGLLFLAGARLWQFFALVFAGILAVVALIVFEEYRMKRVTSFLDPWADPF
GAGYQLTQSLMAYGRGNWFGQGLGNSLQKLEFLPEAHTDFVMAILAEELGFVGVLAVLGL
ILWMVLRALSIGNKALEKGRAFDGYMAYSIGIWFSFQTAVNIGASAGILPTKGLTLPLVS
YGGSSLIIMSVAVAILLRIDFELRVDGVQAIGRGDSKSGKSKARRKKPIPTSASQTKASQ
AEGEASVESGADEADFSTATVEAKPSAKTSSAEDEGKAGIKAILARVAQEADNG